Barstow is a city in San Bernardino County, California, in the Mojave Desert of Southern California. Located in the Inland Empire region of …Barstow is a city in San Bernardino County, California, in the Mojave Desert of Southern California. Located in the Inland Empire region of California, the population was 25,415 at the 2020 census. Barstow is an important crossroads for the Inland Empire and home to Marine Corps Logistics Base Barstow.
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