These first-generation antihistamines commonly cause drowsiness because they interrupt the circadian rhythms that control your normal feelings of sleepiness. In the 1980s, the second generation of ...

Clinical trials are the best indicator of the effectiveness, safety and tolerability of an antihistamine in the treatment of allergic diseases. In contrast to controlled allergen chamber studies ...

The lead candidate, EPX-100, is a first-generation antihistamine with a long history of safe use. Epygenix identified the potential to use the drug to treat Dravet syndrome by screening 3,000 ...