Safe and effective gene therapy strategies depend on robust and reliable adeno-associated virus (AAV) mediated therapeutic gene delivery. However, scaling up AAV manufacturing to obtain sufficient ...

Previous efforts to circumvent the problem of the size limitation imposed by the AAV vector have focused mainly on altering the candidate genes into ‘mini-expression cassettes’ suitable for ...

4 For instance, different AAV serotypes are better able to transduce particular ... researchers can also rely on off-the-shelf plasmid and viral vector solutions, such as those offered by Charles ...

The award is given to scientists who have at least one plasmid deposited that has been distributed at ... and we have expanded our services to offer AAV, first-generation adenovirus (FGAd), ...

AAV-1, 4, and 7,8 originate from non-human primates ... Viral infection and transfection platforms are primarily used to manufacture rAAVs. Plasmid temporary transfection of the human embryonic ...

The AAV Edge System offers a comprehensive suite ... GMP-banked HEK293 host cell line; an optimized two-plasmid system ...

OXB to present at the Leerink Partners Global Healthcare Conference Oxford, UK – 26 February 2025: OXB (LSE: OXB), a global quality and ...