“Our new therapy can induce repair in a tissue that does not naturally ... To test its effectiveness, researchers applied the material to cartilage defects in the stifle joints of sheep, which ...

location and condition of the cartilage defect. “Cartilage repair focuses on addressing the damaged surface of the knee joint, improving its natural cushioning and smoothness,” he said.

An example of the repair of articular cartilage defects by use of a hydrogel seeded with MSCs is presented, to highlight the current strategies, limitations and perspectives of using MSCs to treat OA.

Gillogly SD, Newfield DM. Treatment of Articular Cartilage Defects of the Knee With Autologous Chondrocyte Implantation. MedGenMed 2(2), 2000 [formerly published in Medscape Orthopaedics & Sports ...

The ex vivo cartilage defect model was prepared from cartilage harvested from the KRS patients’ excised knee joints. Only cartilage from the mid-region of the lateral-femoral compartment ...

Figure 1: Application of adult MSCs to tissue engineering, illustrated by several approaches to articular cartilage repair. Cell-based tissue engineering is one of the most promising approaches in ...

The procedure also involved a mosaicplasty — a transplant of tissue harvested from a less-demanding area of the knee to cover a cartilage defect in a more important area — to repair the joint.