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An investigational therapeutic vaccine showed clinical effectiveness in patients with human papillomavirus (HPV)16-positive ...
Last month, the company reported topline data from the Phase III trial of Cevira in participants with cervical high-grade squamous intraepithelial lesions (HSIL). The study achieved its primary ...
CIN: Cervical intraepithelial neoplasia ... Expression of E6/E7 oncogenes increases with the severity of the lesion. In cervical carcinoma the virus is integrated into the host cell chromosomes ...