Comparison of expression data requires normalization. The optimum normalization method depends on sample type, with the most common being to normalize to reference genes. It is critical to select ...

This paper considers inference for both spatial lattice data with possibly irregularly shaped sampling region and non-lattice data, by extending the recently proposed self-normalization (SN) approach ...

Remove unwanted variation (RUV) is a new statistical method for RNA-seq data normalization that uses control genes or samples to improve differential expression analysis.