Focusing development efforts for cancer-preventive drugs on precancerous lesions (that is,intraepithelial neoplasia (IEN)) can reduce costs and accelerate the emergence of new cancer-preventive drugs.
The Anal Cancer/High-grade squamous intraepithelial lesions Outcomes Research (ANCHOR) trial demonstrated that treating precancerous anal HSIL reduces the incidence of anal cancer by 57% in people ...
of whom 18.2% had HPV-negative results and negative intraepithelial lesion or malignancy (NILM) cytologic findings and 25.5% had abnormal results, reported Jasmin Tiro, PhD, of the University of ...
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A therapeutic HPV vaccine could eliminate precancerous cervical lesions, clinical trial suggestsLesion size was significantly reduced in all ... a therapeutic vaccine for patients with HPV16-positive high-grade cervical intraepithelial neoplasia: a Phase II trial, Clinical Cancer Research ...
The incidence of cervical intraepithelial neoplasia (CIN ... A large majority of high-grade lesions in the female genital tract emerge as monoclonal cell populations derived from the cervical ...
Abstract Thinking and Statins With Immune Checkpoint Inhibitors: Enough to Change Clinical Practice? Using an index designed and validated for use in ANCHOR, HRQoL was assessed before random ...
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