The European drug authority recommends refusal of marketing authorization due to evidence gaps in quality and efficacy.

In a second surgery, these cells are implanted into the defect in the patient’s knee. While a successful transplant can last 15-20 years, without treatment, the patient can develop ...

For nearly three decades, Mayo Clinic researcher Christopher Evans, Ph.D., has pushed to expand gene therapy beyond its ...

Teenagers and young adults are increasingly suffering knee injuries, often causing damage to the cartilage. But there's a less invasive procedure called MACI Arthro that's now being used to repair ...

The main finding of this study shows an increase in the size of a cartilage defect between surgeries with increased delays to second-stage autologous chondrocyte implantation/matrix autologous ...

Treatment of Articular Cartilage Defects of the Knee With Autologous Chondrocyte Implantation Scott D. Gillogly, MD, and Daren M. Newfield, MD, practice at the Atlanta Knee & Shoulder Clinic ...

In the new study, the researchers applied the material to damaged cartilage in the animals' knee joints. Within just six months, the researchers observed evidence of enhanced repair, including the ...

“The beauty of this procedure . . . is that you can restore an area that has no cartilage left by putting in a patient’s own normal cells,” orthopedic surgeon says.

In an FDA-observed investigational, new drug, phase 2B study, Anz and his colleagues randomly assigned 81 patients with cartilage defects of the knee greater than 3 cm2 to receive treatment with ...

Injecting the thick, paste-like material into the defects, it formed a rubbery matrix, promoting the growth of new, high-quality cartilage as the scaffold gradually degraded.

Damage to knee cartilage and bone can limit mobility and cause chronic pain. Now, researchers have developed an off-the-shelf synthetic ‘plug’ that heals the joint and could be an alternative ...