This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

Due to their similarities to bacteria, mitochondria can actually trigger severe illness in humans. How can organelles inside our bodies suddenly become a threat? What evidence did Margulis use to ...

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other ...

Scientists at Sanford Burnham Prebys and the Mayo Clinic used cryogenic electron microscopy to create 3D images detailing the overall structure of ubiquitous mitochondrial creatine kinase.

with their cryo-EM structures and mechanisms revealed, providing insights for drug development against intracellular pathogens. Cheng et al. identify a mitochondrial complex IV (CIV) deficiency in ...