Before the discovery of agents that specifically inhibited osteoclastic bone resorption, there was no effective treatment for Paget's disease. This situation changed with the development for ...

Dear Reader: The full name of the condition you have been diagnosed with is Paget’s disease of bone. Also known as osteitis deformans, it is a chronic bone disorder. When someone has Paget’s ...

The disease seems to occur in one of two patterns ... right infraorbital fissure, right maxillary bone, lacrimal bone, malar process and zygomatic bone. These bones were soft, suggesting that ...

Intensive bisphosphonate treatment does not confer a clinical advantage over treatment of symptoms alone in patients with Paget disease of bone. Findings from a UK study reveal that maintenance of ...

Paget’s disease of the breast is a rare kind of breast cancer that mostly affects the skin around the nipple. It happens in only a small number of breast cancer cases because it’s linked to ...

Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early research shows that taking ipriflavone might decrease bone pain in some ...

Paget’s disease of the vulva is a rare type of skin disease that develops on the vulva. It is very slow to spread and is typically found in women who have been through menopause. In some cases, ...

rapid bone growth and exposure to ionising radiation can increase the risk of developing this disease. In some cases, the occurrence of this cancer is due to Paget's disease. Genetic factors also ...

X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Dear Doctors: I was recently diagnosed with Paget’s disease after suffering fatigue symptoms and muscle soreness in my neck, pelvic and lower-leg areas. I am sore and lethargic upon waking up in ...