For patients with mainly mild posterior circulation ischemic stroke, alteplase administered at 4.5 to 24 hours after onset results in higher frequency of functional independence.

In the Phase III EXPECTS trial, patients experiencing mostly mild posterior circulation ischemic stroke who were ineligible ...

The effects and risks of the use of intravenous thrombolysis between 4.5 and 24 hours after the onset of a posterior circulation ischemic stroke are not well studied. In a trial conducted in China ...

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However, health practitioners have known for some time that FAST misses around 20% of stroke types, specifically those affecting the posterior circulation (the back of the brain). These strokes ...

2005).The preferential involvement of the parietal and occipital lobes is thought to be related to the relatively poor sympathetic innervation of the posterior circulation. One characteristic of ...

Researchers found that the percentage of patients with functional independence at 90 days was higher in the alteplase group vs the standard treatment group. HealthDay News — For patients with ...

More information: Shenqiang Yan et al, Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2413344 Journal ...