SMU looks to stop its five-game skid when the Mustangs play Louisville. Thursday's matchup is the first of the season for the two squads.

Take a look at how the Cardinals stack up against the Mustangs for their Tuesday matchup, and who the statistical models favor:

BOTTOM LINE: SMU plays Louisville looking to stop its three-game home skid. The Mustangs have gone 7-4 at home. SMU averages 14.3 turnovers per game and is 4-4 when it wins the turnover battle. The Cardinals are 7-2 in ACC play. Louisville is ninth in the ACC scoring 33.3 points per game in the paint led by Nyla Harris averaging 6.3.

Analyzing Tuesday’s Louisville at SMU odds and lines, with college basketball expert picks, predictions and best bets.

SMU football played a soft ACC schedule last season, while Louisville played the toughest slate. It'll be a bit more even for the top teams in 2025.

Cal faces SMU. Our college basketball odds series has our Cal SMU prediction, odds and pick for Wednesday. ClutchPoints is not affiliated with, endorsed by, or in any way connected to any sportsbook. Gambling is not offered on this website in any form.

The forward has dealt with a broken thumb for the last month, and had to sit the Cardinals' previous game vs. Virginia.

Kentucky; Tuesday, 7 p.m. EST BOTTOM LINE: No. 25 Louisville hosts Wake Forest after Reyne Smith scored 30 points in Louisville's 98-73 win against the SMU Mustangs. The Cardinals are 8-3 on their ...

Pat Kelsey wanted to talk SMU’s ability to win five of its seven Atlantic Coast Conference games for coach Andy Enfield

Louisville celebrated its return to the AP Top 25 in a big way Tuesday night in Moody Coliseum in Dallas, obliterating SMU with a dazzling performance in an astonishing 98-73

Wake Forest Demon Deacons (15-5, 7-2 ACC) at Louisville Cardinals (15-5, 8-1 ACC) Louisville, Kentucky; Tuesday, 7 p.m. EST BETMGM SPORTSBOOK LINE: Cardinals -7.5; over/under is 142 BOTTOM LINE: No. 21 Louisville faces Wake Forest after Reyne Smith scored 30 points in Louisville's 98-73 victory over the SMU Mustangs.

After SMU’s blowout loss to Louisville at home last week, Mustang forward Matt Cross reached his limit. “I think at some point you just have to get sick and tired of getting pushed around on the boards,