In a new study on mice, an experimental antibody treatment reduced the lingering after-effects of head injuries.

TBI occurs when the brain is damaged by an external force, like a nasty tackle or a hard punch (or getting pulled over by your dog ). This can trigger the activation of microglia, the brain’s specialist immune cells. In turn, they produce a bunch of molecules that promote inflammation in the brain.

A study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI,

A treatment tested by researchers in Boston found it improves motor function, coordination and spatial memory in mice. But it still must pass human trials.