INOVIO (NASDAQ: INO) has announced notable interim findings from a Phase 1 clinical trial testing DNA-encoded monoclonal ...
The award is given to scientists who have at least one plasmid deposited that has been distributed at ... and we have expanded our services to offer AAV, first-generation adenovirus (FGAd), ...
4 For instance, different AAV serotypes are better able to transduce particular ... researchers can also rely on off-the-shelf plasmid and viral vector solutions, such as those offered by Charles ...
Safe and effective gene therapy strategies depend on robust and reliable adeno-associated virus (AAV) mediated therapeutic gene delivery. However, scaling up AAV manufacturing to obtain sufficient ...
AAV-1, 4, and 7,8 originate from non-human primates ... Viral infection and transfection platforms are primarily used to manufacture rAAVs. Plasmid temporary transfection of the human embryonic ...
Previous efforts to circumvent the problem of the size limitation imposed by the AAV vector have focused mainly on altering the candidate genes into ‘mini-expression cassettes’ suitable for ...
OXB offers a vast number of unique technologies for viral vector manufacturing, including a 4th generation lentiviral vector system (the TetraVectaâ„¢ system), dual plasmid system for AAV production, ...