In this article, the author modestly expresses his views on the use and understanding of linearity, a key parameter to be determined in analytical method validation in quality control laboratories (QC ...

The area under the busulfan concentration vs time curve (AUC) was calculated using the following equation: AUC = 45C 1h + 15C 1.5h + 270C 1.5h / (ln C 1.5h − ln C 6h) where C 1h, C 1.5h and C 6h ...

Furthermore, we determined that the variable of CRP > 62.8 mg/L did not increase the prediction performance of the APACHE II score using the AUC-ROC comparison by the DeLong method.

Antibacterials are often divided into 2 groups-either time-dependent or concentration-dependent agents-on the basis of their mechanism of killing. Fluoroquinolones are concentration-dependent agents, ...