A majority of patients with ANCA-associated vasculitis had coronary artery calcium on CT scans ... Future studies are warranted to delineate relative contributions of proposed mechanisms of ...

Birmingham Vasculitis Activity Scores (BVAS) were used to identify disease manifestations. Key efficacy outcomes included remission at week 26, sustained remission at week 52, relapse rates, the ...

A new Cedars-Sinai study demonstrates how gut bacteria can influence the development of blood vessel inflammation in ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Background Genetic factors may influence the pathogenic pathways leading to antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We performed a meta-analysis to determine the ...

Objectives Superb microvascular imaging (SMI) provides a more sensitive assessment of small vessels compared with power and colour Doppler ultrasonography (PDUS and CDUS). We aimed to investigate the ...

IgPro10 exact mechanisms of action are still a matter of investigation, some authors propose multiple mechanisms such as natal Fc receptor inhibition, pathogenic antibody neutralization, ...

12 Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece 13 Department of Medicine, Tufts University School of Medicine, Boston, USA 14 Harvard School of ...

Primary membranous nephropathy (PMN) is the most common cause for adult nephrotic syndrome. Rituximab has demonstrated promising clinical efficacy by random controlled trials and the off-label use is ...