Hyalofast consistently demonstrated improvements over microfracture, but missed on statistical significance of the ...

The European drug authority recommends refusal of marketing authorization due to evidence gaps in quality and efficacy.

The articular cartilage is avascular and cannot heal spontaneously when damaged. If left untreated, the damaged cartilage can continue deteriorating into osteoarthritis, eventually requiring a total ...

The Cartilage Repair Registry periodic report from February 1999 documents the results in 588 patients with 12-month, 220 patients with 24 month, and 40 patients with 36-month follow-up. [45] ...

Supplementary Information. Elizabeth A Aisenbrey, Andrew Tomaschke, Eric Kleinjan, Archish Muralidharan, Cecilia Pascual-Garrido, Robert R McLeod, Virginia L. Ferguson, Stephanie J Bryant, “ A ...

AMIC is indicated for patients aged 18 to 50 years for treating knee cartilage defects up to 15 cm 2 located anywhere in the knee — on the medial/lateral condyle, trochlea or patella.

Matrix-associated chondrocyte implantation (MACI) – Used for larger cartilage defects, this is the therapy of choice in the U.S. and involves two surgeries.

An in vivo rabbit model of cartilage defect was used to test the hydrogel’s repair performance. After implantation, tissue samples were evaluated through histological staining (H&E, Safranin O), ...

About 20 years ago, the field of articular cartilage repair was a new and exciting area for researchers and clinicians with several promising treatments being developed and used. These included ...

To understand why, it can be helpful to think in terms of road repair. If you have a focal defect or injury in the articular cartilage, it's as if you have one or two potholes on a road.