Oh, 53, was a staple on Grey's Anatomy from its premiere in 2005 until her departure at the end of season 10 in 2014. Capshaw, meanwhile, played Dr. Arizona Robbins from seasons 5 to 14, briefly returning for season 20, and Luddington joined the series in 2012.

ALS, also known as Lou Gehrig’s disease, is a degenerative disorder that slowly results in the loss of the ability to walk, speak, swallow, and, ultimately, breathe independently.

Euphoria” and former “Grey’s Anatomy” veteran Eric Dane has announced that he has ALS but will continue working