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Described herein is the discovery and development of a process to prepare an atropisomeric intermediate in the synthesis of the KRAS G12C inhibitor sotorasib. Using high-throughput experimentation, (+ ...
A linear transimpedance amplifier (TIA) for a 53 GBd PAM-4 optical link to support 100 Gb/s data on a single wavelength is reported. Designed in a 16 nm FinFET CMOS process, the chip consumes 60.8 mW ...
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During the week of June 9th-13th, the Clark County Extension Office was full of energy, creativity, and the sound of young voices for Baker Intermediate Schools’ first-ever Theatre Camp. This exciting ...
In this segment, the experts discuss the selection criteria among four available JAK inhibitors—ruxolitinib, fedratinib, pacritinib, and momelotinib—for myelofibrosis treatment. Dr. Rampal notes that ...
Today Archer (NYSE: ACHR) joined leaders from the FAA and DOT, including Transportation Secretary Sean P. Duffy and acting FAA Administrator, Chris Rocheleau ...
Snai2 is a transcription factor that inhibits the proliferation of cervical cancer cells and tumor growth.The expression of Snai2 inhibited the expression of β-catenin and impaired Wnt/β-catenin ...
Despite the potential carbon-neutrality of switchgrass bio-oil, its high acidity and diverse chemical composition limit its utilization. The objectives of this research are to investigate pH ...
Tasmanian Labor says it is consulting on what the "right approval process" is for the Macquarie Point stadium, suggesting it may walk back support for the fast-track process proposed by the ...
JERUSALEM (AP) — The Palestinian Authority is heading into a U.N. conference next week hoping to revive a long-defunct peace process. The authority, the Palestinians’ internationally recognized ...
A senior environmental bureaucrat has had her promotion blocked after the panel who chose her botched the hire by not properly taking into account the experience of other candidates, a tribunal ...
176 pages : 28 cm " ... The B2 Upper Intermediate Student's Book gives students further practice in academic study skills. Students analyse characteristics of written and spoken academic texts, ...