A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing Factor ...

A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing ...

Researchers at the University of Cologne have identified the key mitochondrial protein AIFM1 as a central coordinator of ...

Global Phase 2b PRIZM Study of Zagociguat is Currently Enrolling Participants with MELASCAMBRIDGE, Mass., June 17, 2025 (GLOBE NEWSWIRE) -- Tisento Therapeutics today announced that the U.S. Food and ...

14 Mar 2025. A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, ...

Mitochondrial DNA (mtDNA) quantification is crucial in understanding mitochondrial dysfunction, which is linked to a variety of diseases, including cancer and neurodegenerative disorders. Traditional ...

Cryo-EM shows the full-length human mitochondrial RNase Z complex in various maturation states of mitochondrial tRNA. The structure explains substrate recognition and catalysis, the 5′-to-3′ ...

We used a correlative light and EM dataset (Scholl et al., 2021) to characterize mitochondria within basal dendrites of L2/3 pyramidal neurons of the ferret V1 and relate their abundance near spines ...

How a cell's mitochondria make their own protein factories. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 12 / 221208114829.htm ...

The mitochondrial ribosome, or mitoribosome, ... “Cryo-EM allowed us to identify and isolate individual stages of the assembly pathway from a heterogeneous population of purified complexes, and we are ...

The mitochondrial impairment could also be indicated via reduced expression of mitochondria-related genes from the mitochondrial metabolic pathway. To further investigate the potential relevance of ...

In PNAS, using cutting-edge cellular cryo-EM (Fig. 1A), Leung et al. report structural diversity and conservation of mammalian sperm mitochondria in greater detail. Sperm mitochondria are tethered to ...