Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to ...

Find out what happens to heart cells in space and how their adaptation could revolutionize heart disease treatment.

Breakthrough Cardiac Regeneration Research Offers Hope ... a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' ...

Damage to the genetic material of mitochondria—the mitochondrial DNA ... Such damage also speeds up the aging process. However, the cells are normally capable of identifying such damage and ...

In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small ...

Muscle cells, for example, use tons of energy, causing their mitochondria to release lots of a side product of energy processing: reactive oxygen species such as hydrogen peroxide. These ...

58). It has been proposed that the suppression of Fas-mediated death of hepatocytes that express HCV proteins protects these cells from immune-cell-mediated apoptosis and may contribute to the ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Recent advances in cell reprogramming and refinement of methods for additive ... increased fibrosis due to pathological conditions like MI or hypertension significantly stiffens cardiac muscle and ...

The atrophy process can result in skeletal muscle cell apoptosis, protein degradation, fat deposition, and other pathophysiological changes. Skeletal muscle atrophy not only hinders the recovery of ...

Immunizing mice with an edited Lyme disease-causing bacterial protein effectively protected them against the disease.