When the complexity of the vertebrate immune system was increased to deal with pathogens, it also increased the chances of eliciting autoimmune reactions. As our immune system evolved, pathogens ...

Loss-of-function mutations in the gene (CSTB) encoding human cystatin B, a widely expressed cysteine protease inhibitor, are responsible for a severe neurological disorder known as Unverricht ...

This manuscript reports important findings that the methyltransferase METTL3 is involved in the repair of abasic sites and uracil in DNA, mediating resistance to floxuridine-driven cytotoxicity. The ...

Sarah Vine and Andrew Pierce bring their own no-holds-barred opinions, insights and reaction (clue is in the title) to the biggest stories of the week. New episodes every Wednesday, wherever you ...

There are many relationships between the endocrine organs, leading to a chain reaction when one of them fails to function properly. Conditions in which the immune system is involved, including ...

Computational models of cells cannot be considered complete unless they include the most fundamental process of life, the replication and inheritance of genetic material. By creating a computational ...

To balance an unbalanced equation, you need to add numbers to the left of one or more formulae. Here is one way to work out how to do this for the reaction between nitrogen and hydrogen.

Additionally, the percentage of cells with UNG2 foci also increased upon treatment with hydroxyurea (HU), a ribonucleotide reductase inhibitor that alters nucleotide pools ... and protein. APEX2 ...