The expeditious convergent synthesis of the potent human purine nucleoside phosphorylase inhibitor DADMe-Immucillin-G (3) was achieved via the Mannich reaction. The Mannich chemistry of a series of ...

Uric acid is a natural waste product that the body produces after breaking down purines, which is found in certain foods and drinks. Normally, purines dissolves in the blood and is filtered by the ...

In the present study, a series of novel histone deacetylase (HDAC) inhibitors using the morpholinopurine as the capping group were designed and synthesized. Several compounds demonstrated significant ...

Although, spinach contains purines, which are compounds that can be broken down into uric acid in the body. While its consumption is good, it should be consumed in moderation.

Uric acid issues are far more common than most people realise, but the fix could be as simple as what's on your plate. A nutritionist breaks down the foods that help and the ones that do more harm ...