Discover if drinking 2 alcoholic beverages daily can damage your kidneys over time. Learn the science behind alcohol's impact ...

Raad B. Chowdhury, MD, and Shruti Gupta, MD, MPH, are onconephrologists in the Division of Nephrology at Brigham and Women's ...

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a ...

The kidney is a central organ of the mammalian ... BRN1 commits cells to becoming cells of the Henle's loop and distal tubules. Irx genes, possibly together with BRN1, control the fate of the ...

Early detection and consistent treatment of hypertension is critical in order to combat the development of kidney damage, experts have said. As part of the trial, the team of researchers examined the ...

The distal portions of the nephron, including the distal convoluted tubule (DCT), the connecting tubule (CNT ... and the analysis of the consequences of kidney-specific gene knockouts on the distal ...

PPDPF was found to be strongly expressed in healthy proximal tubule cells and increased during the early stages of kidney injury in both mouse models and human samples. Experimental loss of PPDPF ...

Flow cytometry analysis rate of normal cell structure after administration of celastrol ... a specific marker for kidney proximal tubule injury, showed similar expression patterns and were ...

In contrast, genes up-regulated in NAT were enriched in kidney structure and function (inorganic ion transmembrane transport, kidney development) and several metabolic pathways (organic hydroxy ...

Cardiac, renal, and metabolic (CRM) conditions are major causes of morbidity and mortality globally. This study aims to explore the relationship between serum uric acid (SUA), hyperuricemia, gout, and ...