TOPLINE: Lorundrostat, a novel aldosterone synthase inhibitor, lowered blood pressure among adults with uncontrolled hypertension in a phase 3 trial, including in treatment-resistant cases.

Bagsværd, Denmark, 12 June 2025 – Novo Nordisk today announced that it will advance subcutaneous and oral amycretin into phase 3 development in weight management based on completed clinical studies.

MOBILIZE-1 is the first Phase 3 study being initiated for V181 as part of a planned robust clinical development program Study will evaluate a single dose of V181 for the prevention of dengue ...

With what Insmed calls an "outstanding" phase 2 win for its treprostinil palmitil inhalation powder (TPIP) in patients with pulmonary arterial hypertension (PAH), the company is racing to phase 3 ...

Key takeaways: Use of alternative endpoints in phase 3 oncology trials continues to increase. Just 28% of trials published in the past 20 years demonstrated OS improvement.

Cartesian Therapeutics enrolls first participant in Phase 3 trial of Descartes-08 for myasthenia gravis treatment.

Intellia reports a grade 4 liver enzyme elevation in a Nex-Z trial patient; no hospitalization is required, and enrollment remains on track across programs.

WaveLINE-003: Phase 2/3 trial of zilovertamab vedotin plus standard of care in relapsed/refractory diffuse large B-cell lymphoma.. If you have the appropriate software installed, you can download ...

Breztri Aerosphere, a triple inhaled therapy, met its primary endpoint of lung function improvement in adults and adolescents with uncontrolled asthma in two phase 3 trials, according to a press ...

In the current ongoing phase 3 trial, we found evidence for the superiority of semaglutide over placebo for histologic reductions in steatohepatitis and fibrosis.