England have suffered significant injury news ahead of the Six Nations with Jamie George set to miss their opening fixture against Ireland. Hooker George, who has been replaced by Maro Itoje as captain,

England lose Jamie George for Six Nations opener as injuries mount before Ireland clash - Alex Mitchell is also doubtful for Dublin trip, with Alex Coles, Jack van Poortvliet and Alex Dombrandt all ru

England prop Jamie George limped out of Sarcens' 32-24 defeat to Castres in the Champions Cup on Sunday, just weeks before the 2025 Six Nations is set to begin.

Vice-captain Jamie George heads England withdrawals for Six Nations opener - Influential scrum-half Alex Mitchell is a doubt for the opener against Ireland on February 1.

Former England captain Jamie George is now a major injury doubt for the Six Nations after picking up a knock in Saracens’ shock 32-24 defeat to Castres last night. George was named England captain ahead of last year’s Championship,