Announcing the 2025 HDBuzz Prize for Young Science Writers – sponsored by the Hereditary Disease Foundation!

In cells without the HD gene, HTT stimulates PARylation and promotes efficient DNA repair. However, in HD, the mutant HTT protein fails to stimulate PARP, leading to fewer PAR chains, impaired DNA ...

From vision changes to genetic traffic jams and a clinical trial update, May was full of HD science excitement! Dive into our latest roundup to see how researchers are advancing Huntington’s ...

Seeking dental care and adhering to recommended routines is tough for lots of folks, even under the best of circumstances. Throw Huntington’s disease (HD) into the mix, and oral health can get even ...

Votoplam belongs to a class of drugs known as splice modulators. The drug can be taken as a daily pill - a convenient and non-invasive method of delivery. The drug is a chemical that changes how the ...

Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t ...