clinicaltrialsarena23h
Neurocrine Biosciences initiates trial of VMAT2 inhibitor in healthy adults
NBI-1140675 is under development for treating certain neuropsychiatric and neurological conditions. Credit: SewCreamStudio/Shutterstock. Neurocrine Biosciences has ...
clinicaltrialsarena23h
Persica’s antibiotic-based drug alleviates lower back pain in Phase Ib trial
Persica is looking ahead to registrational trials after its antibiotic therapy met the primary endpoint in a Phase Ib trial. Image credit: Shutterstock / New Africa. Persica Pharmaceuticals will ...
Clinical Trials Arena1d
FDA puts clinical hold on BioNTech’s malaria vaccine trial
The US FDA has ordered BioNTech to immediately halt its Phase I/II trial of BNT165e, a malaria vaccine candidate, pending ...
clinicaltrialsarena1d
PepGen pauses Phase II DMD trial to review safety data
PepGen’s stock, which is listed on the Nasdaq market, dropped by 18% after the company announced the news. Image credit: Andrii Yalanskyi / Shutterstock PepGen is pausing the initiation of a new Phase ...
clinicaltrialsarena1d
Bloom Science’s obesity therapy sustains weight loss after final dosing
The safety and efficacy study recruited 32 healthy adults ranging in body weight from healthy weight to overweight. Credit: Shutterstock / leolintang. Bloom Science’s trial examining its primary ...
Clinical Trials Arena2d
Biohaven’s pivotal bipolar drug trial fails, stock takes hit
Biohaven’s pipeline drug BHV-7000 has failed to meet the primary endpoint in a pivotal Phase II/III bipolar trial.
clinicaltrialsarena2d
Daiichi Sankyo and AstraZeneca’s Enhertu shows OS improvements in Phase III trial
DESTINY-Gastric04 claims to be the first Phase III trial to evaluate the ADC in HER2-positive advanced gastric cancer. Credit: SewCreamStudio / Shutterstock. Daiichi Sankyo and AstraZeneca’s Enhertu ...
clinicaltrialsarena2d
Pliant Therapeutics stock tumbles amid IPF trial cancellation
The announcement comes after Pliant confirmed in February 2025 that it would pause the trial awaiting the monitoring board’s decision. Credit: Shutterstock / Lisa F Young Pliant Therapeutics has ...
clinicaltrialsarena2d
CStone doses first subject in trial of CS2009 for advanced solid tumours
The Phase I trial is currently underway in Australia, with plans to extend into the US and China. Credit: Volha_R/Shutterstock. CStone Pharmaceuticals has dosed the first subject in the multicentre ...
Clinical Trials Arena3d
Amgen and AstraZeneca report results from Phase III trial of Tezspire for CRSwNP
Amgen and AstraZeneca have reported outcomes from the WAYPOINT trial of Tezspire for treating chronic rhinosinusitis with ...
clinicaltrialsarena3d
Takeda and Protagonist report topline outcomes from trial of rusfertide
Most PV patients need a regular phlebotomy, which is a blood-removing process for managing increased haematocrit levels. Credit: Orawan Pattarawimonchai / Shutterstock. Takeda and Protagonist ...
clinicaltrialsarena3d
Lexicon’s non-opioid therapy for DPNP beats placebo in pain reduction
The Phase II dose-finding, placebo-controlled Progress study (NCT06203002) enrolled 600 patients living with DPNP. Credit: Shutterstock / Lia_Russy. Lexicon Pharmaceuticals’ non-opioid-based therapy ...