Two to three full-thickness samples of healthy articular cartilage are necessary for culture, weighing 200 to 300 mg or about the volume of a pencil eraser. The biopsy specimen is then placed in ...

Discover how excess weight silently damages your joints through both mechanical stress and inflammation, and learn effective ...

Novartis has terminated a phase 2 trial evaluating an investigational ADAMTS-5 inhibitor for patients with osteoarthritis ...

Osteoarthritis is a common chronic health condition that is characterised by joint pain and restricted movement. The main ...

Restoration of the diseased articular cartilage in patients with OA is ... Professor of Orthopedic Surgery who specializes in knee and hip surgery. He is also Head of the Division of Tissue ...

- CYT-108 is a recombinant protease inhibitor therapy with potential disease-modifying effects - JUPITER, Fla., April 1, 2025 /PRNewswire/ -- Cytonics, an early-stage biopharmaceutical company ...

Osteoarthritis (OA) of the knee is a progressive disease involving the intra-articular (IA) tibia-femoral and patella-femoral cartilage and all other surrounding IA and periarticular structures.1 It ...

A potentially debilitating disease characterized by loss of articular cartilage and resulting joint stiffness and ... with an estimated 1 million knee and hip replacements completed each year.

Methods Knee joints from an inbred C57/BL1/6 (ICRFa ... age accompanied by an increase in the level of oxidative stress and MMP-13 in murine articular cartilage. We modelled these changes using a ...