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Neutralising monoclonal antibodies (NAbs) are being developed for future respiratory virus threats, notably highly pathogenic influenza. They were the first effective antiviral treatments for COVID-19 ...
Post-exposure prophylaxis regimen of rabies monoclonal antibody and vaccine in category 3 potential exposure patients: a phase 4, open-label, randomised, active-controlled trial ...
Monoclonal antibodies can be produced in huge quantities and can be designed to recognize any target. They have become the workhorse for research laboratories.
The extraction system maintained a low concentration of undissociated carboxylic acids in the bioreactor, such as 2.42 mM for undissociated n -caproic acid, 0.01 mM for undissociated n- heptanoic acid ...
However, the mortality wasn’t linked with the cell therapy itself, also known as cema-cel. Instead, Allogene attributed the death to ALL-647, a monoclonal antibody that targets the CD52 protein and ...
Allogene Therapeutics has reported a patient death tied to its anti-CD52 monoclonal antibody used for lymphodepletion in its key CAR-T cell therapy trial for large B-cell lymphoma (LBCL).