The European drug authority recommends refusal of marketing authorization due to evidence gaps in quality and efficacy.

Hyalofast consistently demonstrated improvements over microfracture, but missed on statistical significance of the ...

Supplementary Information. Elizabeth A Aisenbrey, Andrew Tomaschke, Eric Kleinjan, Archish Muralidharan, Cecilia Pascual-Garrido, Robert R McLeod, Virginia L. Ferguson, Stephanie J Bryant, “ A ...

FiberGel is injectable and supports minimally invasive procedures, while the paste-like fibers can fill a random defect with arbitrary geometry before forming a scaffold, facilitating the integration ...

In this study, the researchers produced decellularized cartilage from pigs, characterized it and implanted it in cartilage defects of different pigs – a process known as allotransplantation ...

The Cartilage Repair Registry periodic report from February 1999 documents the results in 588 patients with 12-month, 220 patients with 24 month, and 40 patients with 36-month follow-up. [45] ...

Doctors call this a "defect" -- a worn down portion. If it's two centimeters across and at least half the depth of the cartilage, you would be a candidate for the procedure called MACI -- or ...

Orthopedics > Orthopedics Knee Cartilage Repair Product Wins FDA Nod — First of its kind to be approved, agency says by John Gever, Managing Editor, MedPage Today December 13, 2016 ...

About 20 years ago, the field of articular cartilage repair was a new and exciting area for researchers and clinicians with several promising treatments being developed and used. These included ...

To understand why, it can be helpful to think in terms of road repair. If you have a focal defect or injury in the articular cartilage, it's as if you have one or two potholes on a road.