Cholesterols are converted to cholesteryl esters (CEs) by acyl-coenzyme A and cholesterol acyltransferase (ACAT). The accumulation of CEs provides tumor cells with an abundance of cholesterol for ...

Cholesteryl esters (CEs) and triacylglycerols (TAGs) are stored in lipid droplets (LDs), but their compartmentalisation is not well understood. Here, we established a hyperspectral stimulated Raman ...

This study presents a valuable finding on the importance of the plasma metabolome in glaucoma risk prediction. The evidence supporting the claims of the authors is solid and the work offers insights ...

We therefore screened for the mutations in a test cohort of 1152 individuals from the PROCAM (PROspective CArdiovascular Münster)-Study of North-Western Germany and 2 validation cohorts, 1 from the ...

This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

Most additives are only permitted to be used in certain foods and are subject to specific quantitative limits, so it is important to note this list should be used in conjunction with the appropriate ...

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