Dead to Me's Linda Cardellini opened up to PEOPLE about friend/costar Christina ... the red carpet ahead of the premiere at the Tudum Theater in Los Angeles, Cardellini, 47, discussed Applegate's ...

Christina Applegate ... u MS." According to Page Six Style, Applegate teamed up with manicurist Vanessa Sanchez for the look, which featured a "moody" dark red polish topped with the white letters.