Abstract: Circulating tumor cell detection is crucial for the early diagnosis and treatment evaluation of cancer. Traditional cell detection methods based on bulky instrumentation, while accurate, ...

We aimed to restore MHC-I expression on the surface of solid tumors including breast cancer and melanoma cells to regain sensitivity to immunotherapy and suppress metastatic progression. We screened a ...

Scientists are using artificial intelligence to better capture how healthy cells surrounding tumors influence cancer cell behavior and how those interactions can inform treatments. Even cells ...

State Key Laboratory for Quality and Safety of Agro-Products, School of Material Science and Chemical Engineering, Ningbo University, Ningbo 315211, P. R. China ...

Circulating tumor DNA (ctDNA ... We develop mathematical models of ctDNA kinetics arising from tumor cell population responses to targeted therapy, chemotherapy, and radiotherapy and examine how these ...

Correspondence to Professor Didier Cataldo, Laboratory of Tumor and Development Biology ... experimental mouse model of concomitant pulmonary ozone exposure and tumour cell injection, that ozone ...

Cancer cells that have escaped from the primary tumor are able to invade into surrounding tissues, to intravasate into the bloodstream to become circulating tumor cells (CTCs), and are responsible for ...

A mixture of proteins and other cellular components obtained by breaking open cells. In this study, tumor lysates were used to present a broad array of cancer antigens to the immune system. Overcoming ...

Recently, fascin has been identified in the nucleus of a broad range of cell types but the contributions of nuclear fascin to cancer cell behaviour remain unknown. Here, we demonstrate that fascin ...

To do this, it uses “checkpoint” proteins on immune cells, which act like switches that need to be turned on (or off) to start an immune response. Cancer cells sometimes use these checkpoints to avoid ...