Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

Discover how an emerging technology called tRNA therapy could become the next big thing in genetic disease treatment.

The genomes of species from bacteria to Drosophila show unique biases for particular synonymous codons—varying triplet base pairs that code for the same amino acids—but it has been unclear if such ...

This condition can be both acquired or genetic. Glycosuria can be caused by Fanconi syndrome, due to glucose and amino acids not being able to be absorbed properly as a result of the ...

Stop codons can sometimes be reinterpreted, allowing the cell to insert an amino acid rather than halting translation. This normally requires a specific signal in the mRNA that guides the ribosome ...

That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective at killing both gram-positive and gram-negative pathogenic bacteria, along ...