Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering ...

The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver stage malaria parasites. Cell Host Microbe 4, 567–578 (2008) Article PubMed PubMed Central Google Scholar ...

As important signal metabolites within enterohepatic circulation, bile acids (BAs) play a pivotal role during the occurrence and development of diet-induced nonalcoholic fatty liver disease (NAFLD).

Fatty acid synthase (FASN) is a protein composed of seven subunits (Long and Cravatt, 2011), which is responsible for catalyzing the synthesis of palmitic acid (PA) from acetyl coenzyme A and malonyl ...

The recent finding that the FDA-approved antiobesity agent orlistat (tetrahydrolipstatin, Xenical) is a potent inhibitor of the thioesterase domain of fatty acid synthase (FAS) led us to develop a ...