Objective: Following the introduction and widespread use of central venous catheters (CVCs) in adults, these devices are being used with increasing frequency in the pediatric population.

Alternating lumens or splitting doses for intravenous antibiotic administration in patients with multilumen catheters suspected of CRBSI is recommended. For CRBSI occurring in short-term CVCs ...

A study in patients with solid tumors found that CRBSI is significantly linked to mortality in patients with PICCs, whereas CRT and CRLC are not significant risk factors.