Nature12d
Uridine Diphosphate Glucose: the Coenzyme of the Galactose–Glucose Phosphate Isomerization
A PREVIOUS report 1 dealt with the enzymatic conversion of galactose-1-phosphate into glucose-1-phosphate and mentioned that a thermostable factor is necessary for the reaction. This factor has ...
BMJ13d
The heart in Anderson-Fabry disease and other lysosomal storage disorders
Various disease manifestations may be observed including hypertrophic and dilated cardiomyopathy, coronary artery disease and valvular disease (table 1). Cross-sectional data ... Enzyme uptake is ...
Frontiers13d
Protective Effect of Dictyophora Polysaccharides on Sodium Arsenite-Induced Hepatotoxicity: A Proteomics Study
The purpose of this study is to understand the mechanism of sodium arsenite (NaAsO 2)-induced apoptosis of L-02 human hepatic cells, and how Dictyophora polysaccharide (DIP) protects L-02 cells from ...
thorax.bmj13d
Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
Sphingosine-1-phosphate (S1P) and sphingosine kinase 1 (SPHK1) have been implicated in lung myofibroblast transition, but their role in EMT and their expression in patients with IPF is unknown. The ...
eLife5d
Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells
This important study investigates the signaling pathways regulating retinal regeneration. Convincing evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following ...
Medscape4d
The Role of Kidney in Glucose Homeostasis — SGLT2 Inhibitors, a New Approach in Diabetes Treatment
[1] The purpose of this review paper is to analyze the role of the kidney in glucose homeostasis, emphasizing in SGLT2 inhibition as a new therapeutic target for diabetes management. placebo ...
Investopedia19d
What Is the Average Net Worth of the Top 1%?
Busà Photography / Getty Images Many people believe that being wealthy means having a nice house, a late-model car, and a summer cottage, but the kind of money possessed by the wealthiest 1% of ...
C&EN25d
Redesigned Pathway for De Novo Synthesis of Vanillin and Co-conversion of Multiple Renewable Substrates in Saccharomyces cerevisiae
Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, ...
GSM Arena25d
alcatel 1
Body Dimensions 137.6 x 65.7 x 9.8 mm (5.42 x 2.59 x 0.39 in) ...
Frontiers13d
The Biological Characteristics of Novel H5N6 Highly Pathogenic Avian Influenza Virus and Its Pathogenesis in Ducks
Quantitative reverse transcription PCR (qRT-PCR) results revealed that the immune-relative genes (PRRs, IFNs, Mx-1, IL-6, and IL-8 ... that they preferred to bind to avian-like (α2–3-galactose sialic ...
gut.bmj10d
Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management
Lactase deficiency (LD) is the failure to express the enzyme that hydrolyses lactose into galactose and glucose in the small intestine ... of mammals and lactose (‘milk sugar’; β-galactosyl-1,4 ...