Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1. PLOS ONE, 2019; 14 (11): e0224965 DOI: 10.1371/journal.pone.0224965 ...

To determine the structure of the HIV protein coat (also know as the capsid), the researchers ran simulations at the petascale level using the Blue Waters supercomputer at the University of Illinois.

A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host ...

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