Structural basis of 5′ splice site recognition by the minor spliceosome. Molecular Cell, 2025; 85 (3): 652 DOI: 10.1016/j.molcel.2024.12.017 ...

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

Subsequently, 12.6% of genes that showed alternative splicing in SARS-CoV-2-infected lung tissue were marked to cadherin binding, in three times higher proportion than in the 3.7% gene population ...

If I trained a model to predict a good intron [using] data that is already in nature, we wouldn’t get good rules,” she explained. That meant that “we had to make the data ourselves.” ...