RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA – a prerequisite for protein synthesis in the cell. The poorly ...

Variant c.488A>T (p. Lys163Met), located at the 2nd nucleotide position from the 3′end of exon 4 (216 bp), was predicted to generate a cryptic splice site located at the first 124 bp from the 5′end of ...

Music creation platform Splice has launched Splice Mic, a new feature for its mobile app that allows users to record vocals over instrumentals created within the app. Continue to article... The update ...

Instead, upstream intron length and aberrant splicing in the immediate ... splice sites were extracted and counted using get_alternative_splicing.py. For each splice site, the most abundant splicing ...

the intron-exon bond at the acceptor site, and the bond between the two joined exons after successful exon ligation to yield product RNA (Figure 2A left, Appendix). We refer to these definitions ...

The 3′ Splice Sites in Three Putative IRESs Are Used in Their Native mRNAs. Shown are the number of ESTs in the eIF4G, NRF, and XIAP UniGene clusters that were spliced at the identified site or that ...