Cervical cancer (CC) is the most common cancer affecting women worldwide. Human papillomavirus (HPV) infection is a major contributing factor for the development of CC. The development of CC occurs ...

In most cases, the immune system eliminates HPV and clears the infection. But in some women, the infection persists and leads to cervical dysplasia. Of the more than 100 different strains of HPV ...

Six thousand three studies were screened, 71 full texts assessed, and eight studies met criteria for inclusion, with six included in the final meta-analysis. The sensitivity of S-VIA for the ...

His center has two (2) Florida sites with 84,000 active patients and conducts over 2,000 Pap smears, per month. About Advaxis’ Cervical Dysplasia (CIN) Trial ...

His center has two (2) Florida sites with 84,000 active patients and conducts over 2,000 Pap smears, per month. About Advaxis' Cervical Dysplasia (CIN) Trial Design.

Cervical precancerous lesions are divided into three grades of severity: CIN 1 lesions generally clear up on their own. CIN 2 lesions often clear up on their own, but can also progress to CIN 3 ...

In contrast, HPV types 16, 18, 31, 33, 35, and several others represent an increased risk for dysplasia and are often seen in CIN 1 and CIN 2 lesions as well as in the majority of cervical cancers.

Traditional treatment of CIN 2 and CIN 3 is excisional therapy or ablation of the cervical transformation zone. The disease recurs in 5% to 26% of women, even with negative surgical margins.

2. Ogino I, Kitamura T, Okajima H, et al. High-dose-rate intracavitary brachytherapy the management of cervical and vaginal intraepithelial neoplasia. Int J Radiat Oncol Biol Phys. 1998;40:881-887. 3.

Women who undergo Pap smear tests to screen for cervical cancer one, two or three years after having had normal test results had about the same low rate of significant cellular abnormalities, a ...