Doctors don't really know what causes Paget's disease. It may be a viral infection of the bone, or it could be caused by something in the environment. In about 15% to 30% of cases, there's a ...

Paget’s disease Share on Pinterest Headaches may be a symptom of Paget’s disease. This condition causes a person’s bones to remodel abnormally, leading to bone softening, which can affect ...

When someone has Paget’s disease, it means the process of bone remodeling, which is the cycle of bone growth, has become abnormal. The result is that over time, bones can become larger, weaker ...

PRISM (Paget's disease Randomized trial of Intensive versus Symptomatic Management) was a pragmatic randomized controlled trial, designed to compare the effects of intensive bisphosphonate therapy ...

As bones age, they may weaken or grow abnormally. Osteoporosis and Paget's disease, though different, both affect bone health. Let's understand how are they different in their causes, symptoms, and ...

Original Article from The New England Journal of Medicine — Paget's Disease: Its Pathologic Physiology and the Importance of This in the Complications Arising from Fracture and Immobilization ...