Findings seen in patients with posterior circulation stroke and with no planned thrombectomy who received alteplase 4.5 to 24 hours after stroke onset.

The effects and risks of the use of intravenous thrombolysis between 4.5 and 24 hours after the onset of a posterior circulation ischemic stroke are not well studied. In a trial conducted in China ...

Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. New research findings are summarized in a short video.

However, health practitioners have known for some time that FAST misses around 20% of stroke types, specifically those affecting the posterior circulation (the back of the brain). These strokes ...

2005).The preferential involvement of the parietal and occipital lobes is thought to be related to the relatively poor sympathetic innervation of the posterior circulation. One characteristic of ...

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More information: Shenqiang Yan et al, Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2413344 Journal ...