For patients with posterior circulation stroke, alteplase administered at 4.5 to 24 hours after onset increases frequency of functional independence.

In the Phase III EXPECTS trial, patients experiencing mostly mild posterior circulation ischemic stroke who were ineligible ...

2024 issue of the journal (Circulation. 2024;149:1982–2001. doi: 10.1161/CIRCULATIONAHA.123.065506), corrections are needed. 1. In Supplemental Figure S3F, the right half of immune organ image was ...

Researchers found that the percentage of patients with functional independence at 90 days was higher in the alteplase group vs the standard treatment group. HealthDay News — For patients with ...

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F RIDAY, April 4, 2025 (HealthDay News) -- For patients with mainly mild posterior circulation ischemic stroke who do not receive thrombectomy, alteplase administered at 4.5 to 24 hours after ...

Findings seen in patients with posterior circulation stroke and with no planned thrombectomy who received alteplase 4.5 to 24 hours after stroke onset ...

More information: Shenqiang Yan et al, Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2413344 Journal ...

Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. New research findings are summarized in a short video.

The effects and risks of the use of intravenous thrombolysis between 4.5 and 24 hours after the onset of a posterior circulation ischemic stroke are not well studied. In a trial conducted in China ...

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