In the ever-evolving realm of injectable skincare, a new contender has emerged: polynucleotides. But what exactly are they, and do they live up to the hype swirling around them, especially in ...

There is nervous control of the heart by ATP as a cotransmitter in sympathetic, parasympathetic, and sensory-motor nerves, as well as in intracardiac neurons. Centers in the brain control heart ...

Purine nucleotides have the potential to modulate endothelial cells, platelet activation, leukocyte migration, and cytokine release (14). NO has been reported to regulate the mitochondrial respiratory ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Short-circuitry of brown adipose mitochondria by proton leak through activated human uncoupling protein (UCP1) leads to heat production and this process is thought to be inhibited specifically by ...

Synopsis Short-circuitry of brown adipose mitochondria by proton leak through activated human uncoupling protein (UCP1) leads to heat production and this process is thought to be inhibited ...

Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and answer questions ...

In most organisms, the purine nucleotides are synthesized de novo from non-nucleotide precursors such as amino acids, ammonia and carbon dioxide. An understanding of the enzymes involved in sugarcane ...

The use of 6-mercaptopurine, which targets the purine salvage pathway, led to a reduction in the number of nucleotides and tumor growth.

Extracellular purine nucleotides and nucleosides serve as crucial signalling molecules, acting as neurotransmitters and neuromodulators. Tightly regulated extracellular levels of adenosine ...

Background: Proliferation of vascular smooth muscle cells (VSMCs) is a hallmark of arterial diseases, especially in arterial restenosis after angioplasty or stent placement. VSMCs reprogram their ...