The scientists show how purines and pyrimidines can form from a common precursor molecule that could have existed before life on Earth began. They find 8-oxo-purine shares underlying similarities ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Purines are heterocyclic bases. Simply put, these are closed ring structures comprised of at least two different kinds of atoms. Purines are one of three components of nucleotides; phosphate ...

The team demonstrated how purines and pyrimidine nucleotides can both be assembled on the same sugar scaffold to form molecules called ribonucleotides which are used to construct RNA.

Purines in Cellular Metabolism In addition to their role in nucleic acids, purines are involved in various cellular metabolic processes. Purine nucleotides, such as ATP and GTP, serve as energy ...

Purine nucleotides are essential for cell growth and function as they serve as nucleic acid building blocks, signaling molecules, and energy carriers. Treatments that inhibit their synthesis offer a ...

Xanthine oxidase is an essential enzyme within the uric acid metabolic pathway and is required for the breakdown of purine nucleotides.