Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

The kidney is a central organ of the mammalian ... BRN1 commits cells to becoming cells of the Henle's loop and distal tubules. Irx genes, possibly together with BRN1, control the fate of the ...

Research led by Children's Hospital of Fudan University in China has found that a gene called pancreatic progenitor cell ...

Diabetes-related kidney disease can worsen and lead to failure. You may experience many different symptoms, including lower back pain, fatigue, and nausea or vomiting. If you have kidney disease ...

The exact p-values are also presented in the graphs. Next, we evaluated the staining of the endocytic receptor megalin at the brush border of the proximal tubules. Renal I/R significantly diminished ...

Doctors at Xijing Hospital, affiliated with Air Force Medical University in Xi'an, Shaanxi province, recently transplanted a multi-gene-edited pig kidney into a patient with end-stage renal ...

Kidneys filter waste, regulate blood pressure, and balance electrolytes. A kidney-friendly diet limits sodium, potassium, and phosphorus intake to alleviate strain on the kidneys. Foods like ...

“We know of about 40 genes that play a role in polycystic kidney disease. But these genes have yet to explain the trigger of how you can go from a normal tubule to an elongated tubule to a ...

Researchers at University of Tsukuba have found that the phosphate concentration in proximal tubule fluid, estimated from urine and blood tests, is associated with elevated renal tubular damage ...

Over time, the kidneys may not work as well, and this can lead to kidney failure. The tiny nephrons containing damaged glomeruli and tubules are what doctors view and measure underneath a microscope ...

The developmental mechanisms underlying P-D axis patterning in epithelial tubules are not well understood for any organ. The insect renal (or Malpighian) tubule is a relatively simple epithelial ...