Raad B. Chowdhury, MD, and Shruti Gupta, MD, MPH, are onconephrologists in the Division of Nephrology at Brigham and Women's ...

Cysts, fibrosis, and tubular degeneration form the typical triad of pathologies leading to the gradual decline in kidney ...

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a ...

The kidney is a central organ of the mammalian ... BRN1 commits cells to becoming cells of the Henle's loop and distal tubules. Irx genes, possibly together with BRN1, control the fate of the ...

Early detection and consistent treatment of hypertension is critical in order to combat the development of kidney damage, experts have said. As part of the trial, the team of researchers examined the ...

In comparison to the sham-operated group, mice in the IRI group demonstrated elevated serum levels of blood urea nitrogen (BUN) and serum creatinine (Scr), accompanied by a more pronounced degree of ...

Flow cytometry analysis rate of normal cell structure after administration of celastrol ... a specific marker for kidney proximal tubule injury, showed similar expression patterns and were ...

In contrast, genes up-regulated in NAT were enriched in kidney structure and function (inorganic ion transmembrane transport, kidney development) and several metabolic pathways (organic hydroxy ...

Cardiac, renal, and metabolic (CRM) conditions are major causes of morbidity and mortality globally. This study aims to explore the relationship between serum uric acid (SUA), hyperuricemia, gout, and ...