An Osaka Metropolitan University-led study demonstrated that Cdc42 (cell division cycle 42) plays a crucial role in the formation and maintenance of the morphological characteristics of quiescent ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Scientists at Massachusetts General Hospital have revealed how chronic liver injury alters hepatic stellate cells (HSCs), triggering the formation of fibrotic scarring in the liver. The researchers ...

Restoring stellate cell balance could increase the RSPO3 levels in patients and potentially help the liver regain its normal ...

Parkinson's doesn't just affect movement and the brain—it may also impact the heart, according to new research from the ...

The interplay between aging and cellular senescence reveals insights into chronic inflammation and potential strategies for enhancing healthspan and longevity.

Parkinson's doesn't just affect movement and the brain -- it may also impact the heart, according to new research. Scientists suggest that targeting a key protein outside of the brain could help ...

Researchers at the University of Surrey discovered that Parkinson’s-related alpha-synuclein accumulates in the heart’s nerve ...

More information: Bonn Lee et al, Intact microdissection of stellate ganglia in a Parkinson's disease model reveals aggregation of mutant human α‐synuclein in their cell bodies, Experimental ...